PAULINE C. NG


Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, A1-162, Seattle, WA 98109 USA.

Telephone: (206) 667-4509; Fax: (206)667-5889; email: pauline@howard.fhcrc.org


Education

 

Ph.D. Bioengineering       University of Washington, Seattle WA                                1998-present

(to be received 2002)        Dissertation: “PSSMs: Not just roadkill on the information superhighway”

                        Advisor: Steven Henikoff, Fred Hutchinson Cancer Research Center

           

B.Sc. Biology                Caltech, Pasadena CA                                                      1993-1997

 


Awards

 

Department of Energy Computational Science Graduate Fellowship                              2000-present

 

National Science Foundation Fellowship                                                                 1998-2000

 


Publications

 

Ng, P.C. and Henikoff, S. (2002) Accounting for human polymorphisms predicted to affect protein function.  Genome Research, in press.

 

Ng P.C. and Henikoff, S. (2001) Predicting deleterious amino acid substitutions. Genome Research. 11:863-74.

 

Ng P.C., Henikoff J.G., and Henikoff, S. (2000) PHAT: a transmembrane-specific substitution matrix.  Bioinformatics. 16: 760-6.

 


Extra-mural presentations

 

Ng, P.C., Henikoff, J.G., and Henikoff, S.  PHAT: A transmembrane-specific substitution matrix.  Poster presented at ISMB, U.C. San Diego (2000).

 

Ng, P.C. and Henikoff, S.  SIFT: A sequence-based tool for predicting deleterious amino acid substitutions.  Poster presented at Keystone Symposia: Human Genetics and Genomics, Breckenridge CO (2001).  Scholarship winner.

 


Curricular activities

 

Member of Tau Beta Pi Engineering Honor Society.

Member of Sigma Xi Research Society.

 


Teaching experience

 

Summer 2001     Lecturer, Genotype to Phenotype workshop, Fred Hutchinson Cancer Research Center

Spring 1998       Educational Outreach Intern, Chevron, Richmond, CA

Fall 1996           Teaching Assistant, Undergraduate Biology Course, California Institute of Technology